The sealed sewers is accessed from the central sewers. You must obtain the key called Luke's find, which is found on "Blind" Luke in a room in the Central Sewers or "Sweet" Jill in a room in the East central sewers.
The south part of map contains a room filled with several feral ghouls, including a feral ghoul reaver. Be advised that the reaver is always present, regardless of the player's level.
 Notable loot
- The Humble Cudgel on the corpse of a dead prospector.
- Next to the prospector's corpse there is a fire axe and a duffle bag with various ammunition and loot.
Sealed sewers appears in Fallout: New Vegas.
- It's possible that your follower may get stuck in the entrance of the Sealed Sewer and refuse to move from their location.
Dead Prospector with the The Humble Cudgel.