Lansky was a municipal safety inspector on the monorail construction project. Presumably because she would not let the project go ahead until more safety features were added, she had a hit ordered on her by one of the Boston crime families. Her disappearance was alleged to be a murder by Buster Connolly in his Boston Bugle article "Heaven's Highway - Devil's Doing," and the proof came to light in a holotape by Edward Winter.
Using Operation Winter's End to his own advantage, he bragged about how she was murdered with a pipe wrench by [Vinnie Vannucci|Vinnie "The Crackers" Vannucci]], who also dissolved her in a barrel of hydrocloric acid. In the holotape, he even pointed out the weapon's location; hanging on the wall in Vannucii's Garage, on 4 Prince Street.
Alice Lansky is mentioned only in Fallout 4.