Bo-Peep was an employee of Bysshe Energy and a friend of Calvin van Lowe, whose influence was instrumental in the company agreeing to fund Operation: Mary's Little Lamb, where Calvin would create an impostor sheepsquatch to drive property prices in Lewisburg down and allow the company to buy the town up unmolested. She was responsible for arranging the implementation of a robotics lab below the Van Lowe Taxidermy shop and discreetly transferring property rights to the company, so that the project could continue apace.
The project started in September, with the completion of the lab, and Calvin's work immediately ran into obstacles. Building an impostor sheepsquatch awakened old demons, something that Bo-Peep was not aware of. She wasn't aware of Calvin's dissociative disorders either, at least until Big Bad Wolf, the fixer assigned to her and Blacksheep (Calvin), revealed the classified psych evaluation to her. Troubled by the discovery, she doubted whether she would have pushed this hard for Calvin or the project, but continued, agreeing to meet with Calvin in person for a demonstration at Bastion Park. For his part, Wolf agreed to it and requested that Bo report to him afterwards in person at Beckley for a debriefing.
Problem is, Calvin made a fatal mistake on October 18, 2077, and accidentally overwrote the Assaultron's original programming with his custom sheepsquatch behavioral routines. When Bo arrived at Bastion park, she met a grisly end, vaporized by the Assaultron's head laser. Being dead, Bo missed the meeting, prompting Wolf to act - and eventually struggle to contain the rampaging Assaultron.
Bo-Peep is mentioned only in Fallout 76.