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Jane may refer to:
- "Jackpot" Jane - the manager of Redding's Molerat Mambo in Fallout 2.
- Jane - a Securitron at the Lucky 38 in Fallout: New Vegas
- Jane - an NCR caravan merchant currently squatting in Freeside in Fallout: New Vegas.
- Jane - an employee of Mahkra Fishpacking, mentioned in Fallout 4.
- Jane Myers, the Overseer of Vault 95, mentioned in Fallout 4.
- Jane - the leader of a gang of raiders in Fallout: Brotherhood of Steel.