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Joe may refer to:
- Joe - a Water Merchants guard mentioned in Fallout.
- Joe Jones - a worker at the Mama Dolce's food packaging plant mentioned in Fallout 3.
- Joe Palmer - a resident of Vault 101 in Fallout 3.
- Joe Porter, merchant in Canterbury Commons in Fallout 3.
- Joe Cobb - a Powder Ganger harassing Goodsprings in Fallout: New Vegas.
- Joe - a Bartender in Springfield in Fallout Tactics.
- Joe Grimm - a Eastern Brotherhood of Steel recruit in Fallout Tactics.
- Joey, a small-time thug and drug dealer in The Den in Fallout 2.
- Joey Baxter, a pre-War musician, mentioned in Fallout: New Vegas and its add-on Dead Money.
- Joey Clay, one of the initial resident subjects of Vault 75 in Fallout 4.
- Real-life people
- Joe Sanabria - artist who worked on Fallout: New Vegas.
- Joe Mueller - a Quality Assurance Tester who worked on Fallout: New Vegas.