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Weese was the 21st candidate to be interviewed for overseer of Vault 114. Ever since she was a young girl participating in mock government, she had dreamed of being given the opportunity to lead a community to greatness. Her teachers agreed she had leadership potential: she was head of the debate team, and all the bake sales under her supervision vice president of the student council were a success. Of course, upon telling these anecdotes to the interviewer, he automatically deemed her much too involved for the purposes of the vault's experiment and dismissed her.
Kimberly Weese is mentioned only in Fallout 4.