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Martha may refer to:
- Martha Rastello, the master merchant of the Water Merchants in Fallout.
- Martha Simpson, an inhabitant of Vault 112 in Fallout 3.
- Martha Wilson, an inhabitant of Andale in Fallout 3.
- Martha Linehan, a pre-War American citizen who was accepted into Vault 114. She is mentioned in Fallout 4.
- Martha McDonough, the wife of Patrick McDonough and mother of Mayor McDonough of Diamond City, mentioned in Fallout 4.
- Martha Dilbert, a citizen of Junction City in Fallout Tactics: Brotherhood of Steel.