|The following is based on Van Buren and has not been confirmed by canon sources.|
Mutant cannibals are one of the results of environmental disaster in the Grand Canyon. Their mutation is characteristic for the place of its origin. Mutant cannibals are about 5 ft. tall. While their jaws remained normal-sized, the craniums are visibly oversized. Moreover, their fingers are very long and their nails turned to claws. Dark skin and bulging eyes are also typical.
Mutant cannibals did not appear nor were mentioned in any published games, but were to appear in Van Buren, the canceled Fallout 3 by Black Isle.