One Eye is one of the Fallout GURPS disadvantages (see: Fallout GURPS).
You have only one good eye; you may wear a glass eye, or cover the missing eye with a patch. You suffer a -1 DX penalty on combat and anything involving hand-eye coordination, and a -3 to use missile weapons, throw objects or drive any vehicle faster than a horse and buggy. You will also suffer a -1 on any reaction roll except with utterly alien creatures. Exception: If you have Charisma, or are Handsome or Very Handsome, the patch just looks romantic, and does not affect reaction rolls.”— Steve Jackson Games GURPS sources
With the abandonment of GURPS, the image used for One Eye was recycled for the blinded affliction.