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Rose's syringer is a non-automatic rifle in Fallout 76.

Characteristics[]

During the Flavors of Mayhem quest, Rose requires the player character to shoot the syringer at an enemy, with the intention that the player character will hide during the 30 seconds that the enemy is temporarily buffed, and then easily kill the enemy while it is weakened during the subsequent 60 second period. This weapon will not work on robots, only on enemies that are "flesh and blood."

However, this weapon is equally effective with other teammates to give them a temporary buff for 30 seconds, with the understanding that during the subsequent minute, they will temporarily become more vulnerable to enemy attacks.

Karma syringe details
  • Buff (30 seconds):
    • +15% damage, +50 max HP, +25 DR, ER and RR.
    • Does not work on essential NPCs, scorchbeast queen, wendigo colossus or any robot/turret.
  • Debuff (60 seconds after buff expires):
    • -50% unarmed damage, -100 DR, ER and RR.
    • 100 magnitude stagger (1–2 seconds).
    • Only works on players or yao guai.

Weapon modifications[]

Barrel
ModDescriptionRange changeAccuracy changeAP cost changeRequirementsResources
Karma syringe barrelMakes the target incredibly powerful for 30 Seconds, but incredibly weak for 60 Seconds when it wears off.+120+7
Firecracker berry x2
Glowing resin x1
Psycho x1
Steel x1

Locations[]

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