Sara Samir was a ghoul refugee who joined up with Lucy Harwick at Valley Galleria, to find a home. Unlike her sister, Nari Samir, Sara was a ghoul and was met with fear, prejudice, and violence elsewhere. She became a core member of the community and when Duncan McKann threatened the collective, she followed Lucy to the new hideout at Dyer Chemical. That decision proved to be her undoing, as Sara was slain there together with Lucy and the other ghouls by the vengeful Duncan.
Sara Samir appears only in Fallout 76.