Sylvia Cooper was a denizen of University Point, and one of the few who weren't consumed by fear when the Institute came knocking. She loved Jacqueline like her own daughter and suggested to her father, Gerald, to flee the city and the Commonwealth while they still could. Unfortunately, the Spencers did not listen - or did not have the time to listen. Although she did try to console her in an email, which was eventually deleted.
After Jacqueline repaired the email, Sylvia's network port began to act up. While searching for a replacement, and a new secondary hard disk after her old one blew out the week prior, she found the hard disk that contained research about reactor efficiency.
Sylvia Cooper is mentioned only in Fallout 4.