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Centaurs are misshapen, mutated creatures. They are a by-product of the Forced Evolutionary Virus, as they were created by tossing a varied mix of humans, dogs, cats, brahmin and other animals into an FEV vat and seeing what came out the other end.

Centaurs were created by the Master and frequently travel in large packs with floaters and mutants. They encompassed a large portion of the Master's army.