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Vault 0 (Vault Zero), unlike most vaults involved in the Vault Experiment, was not an experiment in human behavior. It was constructed by expanding and reinforcing the Cheyenne Mountain Complex in Colorado and was by far the largest of the underground Vaults (by volume). If the interiors were so designed, Vault 0 could easily support a population of well over 100,000 people. Many of the areas that comprise the massive interior layout of Vault 0 were originally designed to be the size of (and were often compared to) aircraft hangars, warehouses and factories; these zones were for the construction of various machines that were ostensibly designed to serve the vault dwellers.
Vault 0 was intended to be a place where the geniuses of the pre-War United States could be kept in cryogenic stasis, their brains extracted and frozen for the duration of their "residence" in this vault. They were hooked up to a big supercomputer called the Calculator, which was supposed to function in collaboration with the brains of these pre-War geniuses to design and nurture an ideal human society in a post-War U.S. by educating the survivors and residents.