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Powder Gangers are a gang of escaped convicts that routinely raid small caravans in the Mojave Wasteland. Based in the New California Republic Correctional Facility, Powder Gangers were used as prison labor by the New California Republic to build railroads to foster the republic's expansion. The Powder Gangers rose up in 2281 and took the prison by force, being led by Samuel Cooke. Cooke would later leave the prison and put Eddie in charge. The prisoners used to use dynamite to break up rock to make way for the railway, but now they mainly use it to conduct raids. They use conventional small arms too, but Powder Gangers prefer to do things with a bang.